Groton teams up with Agilent

Groton Biosystems supplies a multiplexed Automated Reactor Sampling (ARS-M™) System for the Agilent 1200 Series LC System. The two companies have collaborated to create a closed-loop solution for monitoring cell culture and fermentation near real time in biotech and pharmaceutical systems. The Agilent 1200 Series LC System and the Groton Biosystems ARS help ensure proper feeding of reactors and fermentors, optimizes product yield, and enables companies to follow the FDA's PAT Initiative.

Increase Productivity.  The Groton Automated Reactor Sampling (ARS-M) system and Agilent 1200 Series LC system provide a high level of automation for development, scale-up, and production within biopharmaceutical facilities.  Enjoy labor savings and productivity gains in sampling and assay of reactors.

Increase Sample Frequency.  Market research indicates that most companies do not sample frequently because it is expensive and increases the risk of bioreactor contamination.  However, companies would like to sample more often to acquire improved process knowledge.  The PAT initiative is based on increasing data collection and sample frequency in order to better understand and control process parameters ultimately leading to an improvement in process control, quality and product yield.

Optimize Your Process.  Realize labor efficiency and speed of analysis when compared with traditional manual sampling, manual sample prep, and bench top analysis.  Increase process knowledge through the acquisition of real time data with the ARS and Agilent 1200 Series LC systems.  Online monitoring bridges the gap between the QC Analytical Lab and Method Development/Production by automating the process.  Continuous automated process monitoring allows for labor efficiencies and prompt process decision making ability.