The GPA1000™ is a fully automated, on-line bioreactor process analyzer system designed specifically to address the need for accurate, high speed, and cost effective monitoring of biotechnology reactors. This powerful system can sample a reactor or fermenter, process the sample, perform all assays, and display complete analytical results in as little as 15 minutes for a wide range of measurements including protein titer, nutrient and metabolite assays, and biophysical measurements. This easy to use system is delivered with a comprehensive library of analytical methods suitable for most installations. In a typical installation, the GPA1000 connects directly to the reactor through a proprietary sanitary connection. Samples can be as small as ½ to 5 ml per assay cycle.